Endolysosomal degradation of Tau and its role in glucocorticoid‐driven hippocampal malfunction
http://orcid.org/0000-0003-0007-4248
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Neurobiology and Behavior Graduate Program, Columbia University, New York, NY, USA
http://orcid.org/0000-0002-1319-476X
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Neuroscience, Columbia University, New York, NY, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
http://orcid.org/0000-0002-2387-0258
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
http://orcid.org/0000-0003-0115-0038
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Corresponding Author
E-mail address: [email protected]
http://orcid.org/0000-0003-4263-5576
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Department of Neuroscience, Columbia University, New York, NY, USA
http://orcid.org/0000-0003-0007-4248
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Neurobiology and Behavior Graduate Program, Columbia University, New York, NY, USA
http://orcid.org/0000-0002-1319-476X
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Neuroscience, Columbia University, New York, NY, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
http://orcid.org/0000-0002-2387-0258
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
http://orcid.org/0000-0003-0115-0038
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
Corresponding Author
E-mail address: [email protected]
http://orcid.org/0000-0003-4263-5576
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Department of Neuroscience, Columbia University, New York, NY, USA
- João Vaz‐Silva1,2,3,
- Patrícia Gomes1,2,‡,
- Qi Jin3,‡,
- Mei Zhu3,‡,
- Viktoriya Zhuravleva3,4,‡,
- Sebastian Quintremil3,
- Torcato Meira1,2,5,
- Joana Silva1,2,
- Chrysoula Dioli1,2,
- Carina Soares‐Cunha1,2,
- Nikolaos P Daskalakis6,
- Nuno Sousa1,2,
- Ioannis Sotiropoulos1,2,‡ and
- Clarissa L Waites *,3,5,‡
- 1Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
- 2ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
- 3Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
- 4Neurobiology and Behavior Graduate Program, Columbia University, New York, NY, USA
- 5Department of Neuroscience, Columbia University, New York, NY, USA
- 6Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA
- ‡These authors contributed equally to this work
- ‡These authors contributed equally to this work
*Corresponding author. Tel: +1 212 305 6025; E‐mail: [email protected]

