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Article30 August 2018full access
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Endolysosomal degradation of Tau and its role in glucocorticoid‐driven hippocampal malfunction

João Vaz‐Silva

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA

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Patrícia Gomes

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

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Qi Jin

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA

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Mei Zhu

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA

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Viktoriya Zhuravleva

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA

Neurobiology and Behavior Graduate Program, Columbia University, New York, NY, USA

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Sebastian Quintremil

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA

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Torcato Meira

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

Department of Neuroscience, Columbia University, New York, NY, USA

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Joana Silva

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

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Chrysoula Dioli

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

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Carina Soares‐Cunha

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

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Nikolaos P Daskalakis

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA

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Nuno Sousa

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

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Ioannis Sotiropoulos

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal

ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal

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Clarissa L Waites

Corresponding Author

E-mail address: [email protected]

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA

Department of Neuroscience, Columbia University, New York, NY, USA

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  • João Vaz‐Silva1,2,3,
  • Patrícia Gomes1,2,,
  • Qi Jin3,,
  • Mei Zhu3,,
  • Viktoriya Zhuravleva3,4,,
  • Sebastian Quintremil3,
  • Torcato Meira1,2,5,
  • Joana Silva1,2,
  • Chrysoula Dioli1,2,
  • Carina Soares‐Cunha1,2,
  • Nikolaos P Daskalakis6,
  • Nuno Sousa1,2,
  • Ioannis Sotiropoulos1,2, and
  • Clarissa L Waites *,3,5,
  • 1Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
  • 2ICVS/3B's ‐ PT Government Associate Laboratory, Braga, Portugal
  • 3Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
  • 4Neurobiology and Behavior Graduate Program, Columbia University, New York, NY, USA
  • 5Department of Neuroscience, Columbia University, New York, NY, USA
  • 6Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA
  • These authors contributed equally to this work
  • These authors contributed equally to this work

*Corresponding author. Tel: +1 212 305 6025; E‐mail: [email protected]