A new study shows how plant peptide hormone signaling balances plant growth and immune response via regulation of nitrogen assimilation.

This review summarizes emerging views on how hypoxia-inducible factors control nutrient utilization in the tumor context, mediating stress responses and metabolic competition between cancer and stromal cells.

This review gives us an evolutionary perspective on auxin, a key regulator of plant growth and development.

Centromere localization of licensing factor KNL2 is dynamically regulated during the cell cycle and ensures proper CENP-A levels as epigenetic centromere marker in chicken cells.

The calcium-dependent protein kinase CPK28 phosphorylates glutamine synthetase GS2 at two distinct sites to regulate the phytosulfokine-dependent balance between plant immune responses and growth.

Mechanical strain and growth factor signalling regulate the condensation of Hippo pathway components in Drosophila and mammalian epithelia.

An optimized purification protocol shows that ZIKV-infected cells secrete noninfectious extracellular vesicles that relieve antibody-dependent enhancement of flavivirus infection.

Respiratory pathogen-secreted outer membrane vesicles or lipooligosaccharide activate the cytosolic innate immune sensor caspase-4/11, gasdermin-D-dependent pyroptosis, and the NLRP3 inflammasome in macrophages.

Gut inflammation modulates autophagy-dependent oxylipin metabolism in distant fat cells to trigger the release of anti-inflammatory signals.

Limiting intracellular L-arginine defines metabolic pathway usage in neural stem cells and safeguards neurogenesis in the adult mouse brain.

A newly identified circRNA, CircBtnl1 inhibits the self-renewal of mouse intestinal stem cells through indirect suppression of Sox9 activity.

Interplay of two DNA damage response kinases moderates ROS production from oxidative phosphorylation by temporarily disrupting VDAC2-ANT2 complexes involved in ADP-ATP exchange.

BRD4 regulates T-helper 2 differentiation via the recruitment of PRC2 to promote transcriptional repression of the T-helper 2-negative regulators Foxp3 and Fbxw7.